HOCl Publications
![Inactivation of Prions and Amyloid Seeds with Hypochlorous Acid](http://www.brioglobal.com/cdn/shop/articles/close-up-researcher-working-with-microscope.jpg?v=1647988381&width=1900)
Inactivation of Prions and Amyloid Seeds with Hypochlorous Acid
PLOS Pathogens: Here we show that hypochlorous acid, a disinfectant that is produced naturally by certain cells within the body, has strong anti-prion and anti-amyloid activity. We find that a non-...
Read more![Fibrin Clot Structure and Mechanics Associated with Specific Oxidation of Methionine Residues in Fibrinogen](http://www.brioglobal.com/cdn/shop/articles/blood-clot-red-cells-vein-white-background-scientific-medical-concept-3d-rendering.jpg?v=1647982985&width=1900)
![Oxidative Modification of von Willebrand Factor by Neutrophil Oxidants Inhibits its Cleavage by ADAMTS13](http://www.brioglobal.com/cdn/shop/articles/neturophil.png?v=1647976574&width=1800)
We show in this study that neutrophil-derived oxidants are capable of readily oxidizing the methionine residue at the cleavage site for the VWF-processing enzyme ADAMTS13.
Read more![Hypochlorous Acid as a Potential Wound Care Agent](http://www.brioglobal.com/cdn/shop/articles/dried-wound-skin-hand-white-background.jpg?v=1647987203&width=1900)
Hypochlorous Acid as a Potential Wound Care Agent
HOCl is known to be the major strong oxidant produced by neutrophils, and is a potent microbicidal agent within these cells. Experimentally, it has been estimated that neutrophils stimulated in vit...
Read more![Efficacy of Electrolyzed Oxidizing Water for Inactivating Escherichia coli O157:H7, Salmonella enteritidis, and Listeria monocytogenes](http://www.brioglobal.com/cdn/shop/articles/female-hands-holding-petri-dish-with-bacterial-colonies-agar-agar.jpg?v=1647986147&width=1900)
American Society for MicrobiologySeptember, 1999AbstractThe efficacy of electrolyzed oxidizing water for inactivating Escherichia coli O157:H7, Salmonella enteritidis, and Listeria monocytogenes wa...
Read more![The Inhibition of Bacterial Growth by Hypochlorous Acid. Possible Role in the Bactericidal Activity of Phagocytes](http://www.brioglobal.com/cdn/shop/articles/leukocyte-white-blood-cells-inside-human-vein-3d-render.jpg?v=1647985782&width=1900)
These effects were apparent within 5 min of HOCl exposure, and were not reversed by extensive washings. DNA synthesis (incorporation of [3H]-thymidine) was significantly affected by even a 1 min ex...
Read more![1915 Experimental Observations on the Antiseptic Action of Hypochlorous Acid and Its Application to Wound Treatment](http://www.brioglobal.com/cdn/shop/articles/Field_hospital_WWI_ER.jpg?v=1647986544&width=1536)
In our observations on the hypochlorites we found that hypochlorous acid is a more potent germicide than its salts, and we have accordingly-devised a method in which the free acid is employed as th...
Read more