HOCl Publications

Inactivation of Prions and Amyloid Seeds with Hypochlorous Acid

PLOS Pathogens: Here we show that hypochlorous acid, a disinfectant that is produced naturally by certain cells within the body, has strong anti-prion and anti-amyloid activity. We find that a non-...

Oxidative Modification of von Willebrand Factor by Neutrophil Oxidants Inhibits its Cleavage by ADAMTS13

We show in this study that neutrophil-derived oxidants are capable of readily oxidizing the methionine residue at the cleavage site for the VWF-processing enzyme ADAMTS13. 

1915 Experimental Observations on the Antiseptic Action of Hypochlorous Acid and Its Application to Wound Treatment

In our observations on the hypochlorites we found that hypochlorous acid is a more potent germicide than its salts, and we have accordingly-devised a method in which the free acid is employed as th...