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    Inhalation of Microaerosolized Hypochlorous Acid (HOCl): Biochemical, Antimicrobial, and Pathological Assessment
    Immune Activation

    Inhalation of Microaerosolized Hypochlorous Acid (HOCl): Biochemical, Antimicrobial, and Pathological Assessment

    Inhalation of HOCl-containing aerosols was recently shown to be an effective therapeutic intervention in the treatment of COVID-19 virusinfected pa...

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    Topical Hypochlorite Ameliorates NF-kB-Mediated Skin Diseases in Mice
    Inflammation

    Topical Hypochlorite Ameliorates NF-kB-Mediated Skin Diseases in Mice

    Exposure of human keratinοcytes to 0.005% HOCl for 1 hour prior to TNF-α stimulation eliminated the induction of both genes.

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    Oxidative Modification of von Willebrand Factor by Neutrophil Oxidants Inhibits its Cleavage by ADAMTS13
    Breakthroughs

    Oxidative Modification of von Willebrand Factor by Neutrophil Oxidants Inhibits its Cleavage by ADAMTS13

    We show in this study that neutrophil-derived oxidants are capable of readily oxidizing the methionine residue at the cleavage site for the VWF-pro...

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