HOCl Publications
![Hypochlorous Acid: An Ideal Wound Care Agent With Powerful Microbicidal, Antibiofilm, and Wound Healing Potency](http://www.brioglobal.com/cdn/shop/articles/bloody-wound-palm-arm-wrist-after-accident-fall-sport-injury-painful-hand-wound-accident.jpg?v=1647984834&width=1900)
The aim of this study was to investigate the effect of stabilized hypochlorous acid solution (HOCl) on killing rate, biofilm formation, antimicrobial activity within biofilm against frequently isol...
Read more![The National Necrotizing Fasciitis Foundation Says Current Standard of Care for Flesh-eating Bacteria is "Tragically Inadequate"](http://www.brioglobal.com/cdn/shop/articles/arm-scald-wound-from-hot-water.jpg?v=1647986936&width=1900)
Neutralize toxins that eat away flesh by irrigating the wounds of necrotizing fasciitis patients with a substance called hypochlorous acid (HOCl), a natural chemical produced by white blood cells a...
Read more![Topical Hypochlorite Ameliorates NF-kB-Mediated Skin Diseases in Mice](http://www.brioglobal.com/cdn/shop/articles/cute-rat-table-laboratory.png?v=1647973116&width=1800)
Topical Hypochlorite Ameliorates NF-kB-Mediated Skin Diseases in Mice
Exposure of human keratinοcytes to 0.005% HOCl for 1 hour prior to TNF-α stimulation eliminated the induction of both genes.
Read more![Fibrin Clot Structure and Mechanics Associated with Specific Oxidation of Methionine Residues in Fibrinogen](http://www.brioglobal.com/cdn/shop/articles/blood-clot-red-cells-vein-white-background-scientific-medical-concept-3d-rendering.jpg?v=1647982985&width=1900)
![Hypochlorous Acid as a Potential Wound Care Agent](http://www.brioglobal.com/cdn/shop/articles/dried-wound-skin-hand-white-background.jpg?v=1647987203&width=1900)
Hypochlorous Acid as a Potential Wound Care Agent
HOCl is known to be the major strong oxidant produced by neutrophils, and is a potent microbicidal agent within these cells. Experimentally, it has been estimated that neutrophils stimulated in vit...
Read more![Stabilized Hypochlorous Acid: Its Role in Decreasing Tissue Bacterial Bioburden and Overcoming the Inhibition of Infection on Wound Healing](http://www.brioglobal.com/cdn/shop/articles/male-patient-bandaged-hand-injury-fingers-hospital-medicine.jpg?v=1647987099&width=1900)
This stabilized form of hypochlorous acid (NVC-101) could have potential application as an antimicrobial wound irrigation and treatment solution if its effective pH range can be maintained in the c...
Read more![1915 Experimental Observations on the Antiseptic Action of Hypochlorous Acid and Its Application to Wound Treatment](http://www.brioglobal.com/cdn/shop/articles/Field_hospital_WWI_ER.jpg?v=1647986544&width=1536)
In our observations on the hypochlorites we found that hypochlorous acid is a more potent germicide than its salts, and we have accordingly-devised a method in which the free acid is employed as th...
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